介肠卡斯特曼病:两个病例报告和文献综述
Se-Niu Jizhi1,2, Xing-Yu Chen2, Shan-Shan Wu2
1Department of Clinical Medicine, North Sichuan Medical College, Nanchong 637000, Sichuan Province, China.
World journal of gastrointestinal surgery
|February 16, 2026
概括
间肠卡斯特曼病 (CD) 是一种罕见的疾病. 这项研究详细介绍了两个病例,其中一个转变为外围T细胞淋巴瘤 (PTCL-NOS),强调了多样化的临床过程和个性化管理的需要.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 病理学 病理学 病理学
背景情况:
- 卡斯特曼病 (CD) 是一种罕见的淋巴增殖性疾病.
- 介肠性CD不常见,通常通过组织病理学来诊断.
- 胃肠道症状和体重减轻可能表明中肠干涉.
研究的目的:
- 报告两个独特的中腔卡斯特曼病病例.
- 突出介质性CD转化为外围T细胞淋巴瘤的潜力,未另有说明 (PTCL-NOS).
- 为了强调个性化治疗策略对中腔CD的重要性.
主要方法:
- 关于两名患有中腔CD的患者的病例报告.
- 手术切除和组织病理学检查用于诊断和分类.
- 临床随访,以评估疾病的发展过程和治疗结果.
主要成果:
- 案例1:血管类型CD,切除后的预后良好.
- 案例2:最初是血细胞类型CD,转化为PTCL-NOS.
- 病例2经历了激进的过程,导致由于PTCL-NOS的术后死亡.
结论:
- 这是第一个被报告的介质性CD转化为PTCL-NOS的案例.
- 中腔CD表现出复杂和异质的临床行为.
- 这些发现强调了针对中腔CD的量身定制的治疗和管理方法.
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