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Updated: Feb 17, 2026

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使用患者衍生异种移植模型识别胃癌中潜在有害突变

Luke Kong1,2, Jie Wang1, Junqi Zheng1

  • 1Basic Medical College, Shanxi Medical University, Taiyuan, Shanxi, China.

Frontiers in genetics
|February 16, 2026
PubMed
概括

来自患者的异种移植模型准确地反映了胃癌的遗传格局. 这项研究确定了胃癌中保存的,潜在有害的突变,提供了新的治疗点.

关键词:
生物信息学工具 生物信息学工具有害的突变.胃癌 胃癌 是一种胃癌.患者衍生异种移植 (PDX)整体外因子测序 (WES) 测序

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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