全球范围内的标准化Omics:障碍,机遇和经验教训的视角
Melanie T Odenkirk1, Eunice Afia Amponsah2, Amos Anim2
1Department of Horticulture and Landscape Architecture, Colorado State University, Fort Collins, Colorado 80524, United States.
Analytical chemistry
|February 16, 2026
概括
全球参与奥米克科学受到资源的不平等接入所阻碍. 粮食倡议周期表 (PTFI) 突出显著的物流障碍,特别是低收入和中等收入国家 (LMICs),影响全球数据标准化.
科学领域:
- 奥米克是科学科学的一个领域.
- 分析化学是一种分析化学.
- 数据科学是数据科学.
背景情况:
- 由于分析化学和数据科学方面的创新,omics科学正在迅速发展.
- 公平的全球参与OMIC受到不平等的基础设施,培训和其他障碍的限制.
- 标准化工作对于生成大规模可比数据集至关重要.
研究的目的:
- 通过食品周期表倡议 (PTFI) 进行标准化食品分析工作流程的初步传播,分享从中吸取的经验教训.
- 突出国际合作实验室遇到的障碍,特别是在低收入和中等收入国家 (LMICs).
- 确定实验室采用标准化奥米克学方法的关键驱动因素.
主要方法:
- 向19个国际合作伙伴实验室分发标准化的omics工作流程.
- 质量报告物流挑战和遇到的障碍.
- 在高收入国家 (HIC) 和LMIC之间对试剂运输时间进行比较分析.
主要成果:
- 记录了仪器采购和操作的广泛后勤挑战,特别是在LMICs.
- 试剂运输平均为HIC的4.25天,而LMIC的65.6天,增加了1444%.
- 确定了影响采用标准化omics方法的关键驱动因素,影响全球倡议的可行性.
结论:
- 在全球范围内,科学基础设施存在重大差异,这给OMIC标准化带来了巨大的障碍.
- 民主化omics和确保全球举措的可持续性需要解决这些挑战.
- 国际科学界的集体承诺对于开发全球可访问,端到端的omics工作流程至关重要.
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