通过在现场超快激光减光来定等离子纳米粒子结构,用于超敏感和高度稳定的SERS
Junde Ji1, Luchan Lin1, Yifan Hu1
1Shanghai Key Laboratory of Materials Laser Processing and Modification, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
ACS applied materials & interfaces
|February 16, 2026
概括
这项研究提出了一种新方法,用于使用超快激光器创建强大的表面增强拉曼光谱 (SERS) 基板. 这些基板为环境和生物医学应用提供超敏感的化学检测,具有高稳定性.
科学领域:
- 材料科学 材料科学 材料科学
- 频谱学是一种光谱学.
- 纳米技术 纳米技术
背景情况:
- 表面增强拉曼光谱 (SERS) 对于环境和生物领域的超敏感化学物质检测至关重要.
- 现有的SERS基板经常面临稳定性和可重复性方面的挑战.
研究的目的:
- 开发一种基板独立的方法来制造强大的SERS平台.
- 在各种基板上增强等离子体纳米粒子 (NP) 的粘合强度和稳定性.
主要方法:
- 使用超快激光诱导的多光子减少制造固定的等离子纳米粒子 (NP) 结构.
- 通过增强等离子体效应增强的界面能量沉积来增强NP-基板结合.
- 精确的能量调制来控制Ag NP大小 (20.68 ± 8.68 nm) 和间隙 (< 5 nm).
主要成果:
- 达到了超低检测极限 (晶紫的10~14M, thiabendazole的10~12M).
- 证明了高稳定性:在100天的老化后保留了78.1%的拉曼强度,在10个曲周期后保持了65.9%.
- 呈现出极好的统一性 (RSD 4.29%) 和可重复性 (RSD 7.95%).
- 在生物样本上实现了直接纳米制造,热损伤最小.
- 在120分钟的水流量后,显示了56.9%的信号保留,具有机械强度.
结论:
- 超快激光合成提供了一种多功能,基板独立的方法,用于创建稳定的SERS平台.
- 开发的SERS基板适用于环境监测,生物医学诊断和食品安全方面的苛刻应用.
相关概念视频
01:37Super-resolution Fluorescence Microscopy
Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been developed.
01:07Scanning Electron Microscopy
A scanning electron microscope (SEM) is used to study the surface features of a sample by using an electron beam that scans the sample surface in a two-dimensional manner. Typically, areas between ~1 centimeter to 5 micrometers in width can be imaged. SEM can be used to image bacteria, viruses, tissues as well as larger samples like insects. Conventional SEM gives a magnification ranging from 20X to 30,000X and spatial resolution of 50 to 100 nanometers.
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