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Updated: Feb 18, 2026

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在SARS-CoV-2进入过程中,胆固醇依赖性膜融合的分子机制

Wei Li1, Mengdan Wu1, Shirong Feng1

  • 1National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Signal transduction and targeted therapy
|February 16, 2026
PubMed
概括

胆固醇通过促进尖端蛋白质聚类和病毒对接来增强严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 进入. 这种机制涉及胆固醇与尖端蛋白的C端囊蛋白丰富区域相互作用,促进膜融合.

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