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Updated: Feb 18, 2026

A Reporter Assay to Analyze Intronic microRNA Maturation in Mammalian Cells
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A Reporter Assay to Analyze Intronic microRNA Maturation in Mammalian Cells

Published on: June 16, 2022

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针对性地阻断基因剪接可以调节内部嵌入的初级microRNAs.

Md Hasan Ali1, Athul R Ramesh1, Naveen Nedunchezhian1

  • 1Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Poznań, Poland.

Communications biology
|February 16, 2026
PubMed
概括

针对内基非编码RNA (ncRNA) 的反感性寡核酸 (ASO) 可以意外地增加microRNA的表达,影响神经元发育. 这项研究揭示了ASOs如何影响内基ncRNA,并建议利用这些效应来识别microRNA角色.

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