脱发区域的流行病学,诊断和管理:亚太经过修改的Delphi专家小组的建议
Rodney Sinclair1,2, Chao-Chun Yang3, Wen-Hung Chung4
1Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia.
International journal of dermatology
|February 16, 2026
概括
脱发区的管理现在通过新的指导方针在整个亚太地区得到了标准化. 这一共识提供了用于诊断和治疗大发性脱发症 (AA) 的实际步骤,以改善患者护理.
科学领域:
- 皮肤病学 皮肤病学
- 临床实践指南 临床实践指南
- 脱发障碍 脱发障碍 脱发障碍
背景情况:
- 大发性脱发症 (AA) 显著影响所有人口群体的生活质量.
- 最近的治疗批准 (2022/2023) 需要更新的指南.
- 许多亚太国家缺乏具体或最新的AA管理指南.
研究的目的:
- 制定特定区域的共识指导方针,以诊断和管理白发症.
- 解决亚太地区AA呈现和治疗可访问性的异质性.
- 为管理AA的医疗保健提供者提供一个实际的框架.
主要方法:
- 一个经过修改的德尔菲共识过程,涉及来自亚太地区八个国家的18名皮肤科医生.
- 三轮调查,讨论和声明投票,以达到≥70%的协议.
- 在140个关于AA诊断和治疗的陈述上达成共识.
主要成果:
- 三镜对于AA诊断和监测至关重要;活检仅用于不明确的病例.
- 定义的疾病严重程度:中度AA (21%-49%的脱发),严重AA (≥50%的脱发).
- 治疗建议包括12岁以下儿童的局部皮质类固醇,老年患者的轻度至中度AA的皮质类固醇,中度至重度AA的JAK抑制剂/全身皮质类固醇,以及慢性病例的辅助剂米诺克西德.
结论:
- 一个实用的,以区域为中心的框架,用于在亚太地区标准化AA诊断和管理.
- 旨在通过提供一致的,基于证据的护理来改善患者的治疗结果.
- 强调需要更新的指导方针,纳入新治疗方法的脱发区.
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