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相关实验视频

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Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
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自闭症成年人的反应抑制:在虚拟现实中的功能近红外光谱研究.

Anna Vorreuther1, Nektaria Tagalidou1, Katharina Lingelbach2,3

  • 1Institute of Human Factors and Technology Management IAT, University of Stuttgart, Stuttgart, Germany.

Brain and behavior
|February 16, 2026
PubMed
概括

自闭症和非自闭症成年人在虚拟现实抑制任务上表现相似. 然而,只有非自闭症成年人在任务期间在前额叶皮质中显示出预期的大脑活动变化.

关键词:
自闭症自闭症是什么功能近红外光谱学近红外光谱学抑制抑制抑制的抑制作用虚拟现实 虚拟现实 虚拟现实 虚拟现实

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科学领域:

  • 神经科学是一个神经科学.
  • 心理学 心理学 心理学
  • 虚拟现实 虚拟现实 虚拟现实

背景情况:

  • 执行功能,特别是响应抑制,在自闭症研究中至关重要.
  • 现有研究表明,任务设计影响的结果各不相同.
  • 虚拟现实 (VR) 为研究认知过程提供了新的方法.

研究的目的:

  • 为了比较自闭症和非自闭症成年人的行为和神经生理反应在VR视觉空间去/不去任务 (GNGT) 期间.
  • 使用功能近红外光谱学 (fNIRS) 调查前额叶皮层 (PFC) 活动的差异.

主要方法:

  • 对22名自闭症和10名非自闭症成年人进行了基于VR的GNGT.
  • 收集行为数据 (反应时间,错误率).
  • 使用fNIRS测量了前额头血液动力学反应.

主要成果:

  • 没有观察到行为表现 (反应时间,错误率) 的显著群体差异.
  • 非自闭症成年人在no-go阻塞期间表现出显著的右侧dlPFC激活.
  • 自闭症成年人没有显示PFC活动的与任务相关的显著调节.

结论:

  • 可比较的行为表现掩盖了自闭症和非自闭症成年人之间抑制反应的潜在神经差异.
  • 虚拟现实中的fNIRS可以在执行功能任务期间揭示不同的神经参与模式.
  • 这些发现强调了神经生理学措施在理解自闭症方面的重要性.