在左和右的HF-rTMSDLPFC增强主动认知控制:一个抗和瞳孔测量研究
Aaron Van Boven1, Viviana Verde1,2, Jens Allaert3
1Psychopathology and Affective Neuroscience Lab, Department of Experimental Clinical and Health Psychology, Ghent University, Ghent, Belgium.
Psychophysiology
|February 16, 2026
概括
在左侧和右侧脊侧前额叶皮层 (DLPFC) 上进行高频重复性横磁刺激 (HF-rTMS) 改善了主动性认知控制. 这表明双边的DLPFC参与了对即将到来的任务进行认知资源分配的监管.
科学领域:
- 认知神经科学 认知神经科学
- 神经成像是一种神经成像.
- 人类神经生理学 人类神经生理学
背景情况:
- 积极的认知控制对于预测和准备认知需求至关重要.
- 背侧前额皮层 (DLPFC) 参与主动控制,但其侧面化仍在争论中.
- 了解DLPFC侧面化是完善认知控制模型的关键.
研究的目的:
- 在主动认知控制中研究背侧侧前额皮层 (DLPFC) 的侧向化.
- 检查高频重复性横磁性刺激 (HF-rTMS) 对DLPFC活动和认知控制的影响.
- 探索学生计量在评估主动控制任务期间认知资源分配中的作用.
主要方法:
- 这是一项单盲,模拟控制,主体内随机化研究,涉及31名健康参与者.
- 在左侧和右侧的DLPFC应用主动和假的高频重复性横磁刺激 (HF-rTMS).
- 使用反动任务与瞳孔测量相结合,以测量主动认知控制和资源分配.
主要成果:
- 探索性分析显示,与假的相比,在左和右DLPFC HF-rTMS后,在抗分试验中,固定延迟显著更短.
- 在预测阶段 (阶段性资源分配) 的瞳孔大小在激活左和右DLPFC刺激后更大.
- 较大的预测瞳孔大小与较短的抗固定延迟相关,而强化瞳孔大小的影响因刺激条件而异.
结论:
- 这些发现支持左侧和右侧DLPFC在主动认知控制中的参与.
- 双边DLPFC刺激调节了预期性认知资源分配,正如学生计量所证明的那样.
- 这项研究有助于协调以前关于DLPFC侧向化在认知控制中的混合发现.
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