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Updated: Feb 18, 2026

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代谢物α-甲酸通过脱甲基酶TET2诱导AIM2-依赖的PANoptosis

Yi Li1,2, Qing Tu1,2, Chenchen Liu1,2

  • 1Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China.

Cell communication and signaling : CCS
|February 17, 2026
PubMed
概括

阿尔法-谷氨酸 (α-KG) 通过激活AIM2-PANoptosome通路,驱动炎症和败血症中的细胞死亡. 针对涉及TET2的这种途径,为败血症提供了一种新的治疗策略.

关键词:
在AIM2中,AIM2是AIM2.这就是PANoptosis.败血症 这是一种败血症.在TET2的基础上.α-基格酸盐的使用.

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