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Updated: Feb 18, 2026

Author Spotlight: Advanced Single-Molecule Techniques for Investigating Telomeric Protein-DNA Interactions
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TRF-1 在异位端粒中调解PRC2功能 在Neurospora crassa中重复

Colleen C Mumford1, Peregrine D Painter1, Kevin J McNaught1

  • 1Institute of Molecular Biology, University of Oregon, Eugene, Oregon, USA.

Molecular and cellular biology
|February 17, 2026
PubMed
概括

端粒重复可以通过TRF-1蛋白质诱导抑制性基因素标记 (H3K27me),即使在非原生位置. 这表明TRF-1是端粒序列抑制的关键.

关键词:
G4 DNA DNA DNA 的意思泰洛米尔 (Telomere) 是一种电离体.选择性的异色染色.基因组 H3K27 的甲基化.

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