我们患者的临床,放射和荷尔蒙特征与初级空塞拉:一个单一中心的经验
Adem Kilinc1, Betul Kizildag2, Adem Doganer3
1Department of Internal Medicine, Kahramanmaraş Sutcu Imam University, Faculty of Medicine, Kahramanmaraş, Türkiye.
概括
主要空 (PES) 往往涉及垂体缺陷,全垂体缺陷在总PES中更为常见. 低垂体高度和男性性别是泛垂体缺陷症的关键风险因素,需要对患者进行更密切的监测.
科学领域:
- 内分泌学 在内分泌学.
- 放射学 放射学是一门学科.
- 内部医学 内部医学
背景情况:
- 主要空塞拉 (PES) 是无症状成年人的频繁偶然发现.
- 了解PES患者的临床,放射和激素特征对于风险分层和随访至关重要.
研究的目的:
- 调查诊断为初级空腹的患者的临床,放射和荷尔蒙特征.
- 在PES患者中识别与 pituitary insufficiency 和 panhypopituitarism 相关的风险因素.
- 为 PES 患者提供最佳后续策略的指导.
主要方法:
- 对120名PES患者的回顾性分析.
- 数据收集包括症状,并发症,放射学发现和荷尔蒙测定.
- 根据垂体缺陷的严重程度,患者被分为部分/总PES和孤立的激素缺乏症,下垂体缺陷症或全下垂体缺陷症.
主要成果:
- 激素缺乏症 (HD) 在83.3%的患者中存在,最常见的是生长激素缺乏症和中枢性阴性腺症.
- 与部分组 (30.5%) 相比,在全 PES 组 (60.5%) 中,泛hypopituitarism 的发生率更高.
- 低垂体身高和男性性别被确定为泛垂体病的重要危险因素 (分别为p=0.002和p=0.015).
结论:
- 垂体缺陷是PES的一个常见并发症.
- 泛hypopituitarism 在总的PES中更为普遍.
- 建议对低垂体高度和男性性别的PES患者进行密切监测,因为增加了泛垂体垂体症的风险.
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