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异常的血压浸泡模式在女性下垂体次要的希恩综合征:一个病例对照研究研究
Ibtissem Oueslati1, Salma Salhi1, Emna Talbi2
1Department of Endocrinology, La Rabta University Hospital, Faculty of Medicine of Tunis, University of Tunis-El Manar, Tunis, Tunisia.
概括
患有希恩综合征的妇女经历血压 (BP) 节律的破坏,与对照组相比,血压下降异常和夜间高血压的患病率更高. 这突出了对低垂体病患者的显著心血管影响.
科学领域:
- 内分泌学 在内分泌学.
- 心血管医学 心血管医学
- 高血压研究 高血压研究
背景情况:
- 希恩综合征会导致下垂体,影响荷尔蒙平衡.
- 循环血压 (BP) 模式对心血管健康至关重要.
- 被打扰的血压下降与心血管风险增加有关.
研究的目的:
- 为了评估与希恩综合征的妇女24小时的门诊血压水平.
- 为了确定这个人群中异常的昼夜血压下降模式的患病率.
- 将血压变化和高血压率与年龄和BMI匹配的对照进行比较.
主要方法:
- 横截面研究设计. 截面研究设计.
- 包括35名患有希恩综合征的妇女和47名对照.
- 24小时的门诊血压监测,临床检查和实验室测试.
主要成果:
- 患有希恩综合征的女性表现出更高的失脂血症和代谢综合征.
- 改变日夜血压变化在希恩综合征患者中明显更频繁 (85%对54%).
- 希恩综合征患者的夜间高血压明显高 (38%对3%),并与非低血压/升高血压概况相关.
结论:
- 由于希恩综合征的二次性下垂体病变扰乱了昼夜血压节奏.
- 虽然整体高血压的患病率相似,但夜间高血压是一个关键问题.
- 这些发现强调了在希恩综合征患者中需要警的心血管监测的必要性.
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