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使用Illumina EPIC甲基化数据来推断吸烟状态的EpiSmokEr2:一个强大的表观遗传分类器

Tianyu Zhu1,2,3, Teodóra Faragó1,2, Sailalitha Bollepalli2

  • 1Minerva Foundation Institute for Medical Research, Helsinki, Finland.

Epigenomics
|February 17, 2026
PubMed
概括

一个新的DNA甲基化分类器EpiSmokEr2使用血液样本准确估计吸烟状态. 这种工具提供了一个可靠的生物标志物,用于跟踪长期吸烟暴露在研究中.

关键词:
通过DNA甲基化.拉索回归法 (Lasso Regression) 是一种回归法.生物标志物 生物标志物分类器分类器是分类器.照亮一个EPIC阵列.吸烟状态 吸烟状态

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