饮食,情绪和肠道微生物组在为期八周的潜艇部署期间的相互作用
Zachary Liechty1,2, Blake Stamps3, Mahamat Babagana4,5
1711 Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Dayton, Ohio, USA.
Microbiology spectrum
|February 17, 2026
概括
潜艇的部署改变了肠道微生物组,饮食和情绪. 肠道微生物的变化与饮食和情绪变化相关,影响潜艇员的疲劳.
科学领域:
- 微生物组研究的研究.
- 在极端环境下的人类生理学.
- 太空飞行和极端环境的模拟研究.
背景情况:
- 肠道微生物组的破坏与认知和心理健康问题有关.
- 长时间的潜艇部署涉及压力因素,如限制饮食,改变昼夜节律,睡眠不足和压力,已知会破坏微生物群.
研究的目的:
- 在长时间的潜艇部署期间,表征肠道微生物群,饮食和情绪变化.
- 研究这些因素之间的相互作用及其对潜艇健康和性能的影响.
主要方法:
- 在为期8周的部署期间,在6个时间点收集了34名潜艇员的便和血液样本.
- 使用16S rRNA基因测序分析便样本.
- 通过问卷评估饮食和情绪;分析压力,神经认知,免疫和肠道屏障生物标志物的血液.
主要成果:
- 观察到基线肠道微生物多样性的高个体间变异性.
- 特定的微生物组成显示了个体内与部署相关的变化.
- 微生物群组成的变化与饮食和情绪的变化相关,与疲劳增加有关.
结论:
- 在长时间的潜艇部署期间,肠道微生物组的组成是动态的,受到饮食和情绪的影响.
- 研究结果提供了关于人类适应受限,压力较大的环境的见解.
- 识别了微生物干预的潜力,以提高孤立任务中的弹性.
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