在瑞典的第一代和第二代移民中,骨质疏松性骨折的复发
Per Wändell1,2, Xinjun Li2, Hans Ranch Lundin1,3
1Division of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
概括
与瑞典本土人相比,第一代和第二代移民男性的复发性骨质疏松性骨折风险略低一些. 然而,移民女性具有类似的骨折风险,根据原产地区观察到的差异.
科学领域:
- 流行病学 流行病学
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
背景情况:
- 骨质疏松性骨折对健康造成重大负担,特别是在老年人群中.
- 了解移民群体之间的骨折风险差异对于有针对性的公共卫生干预至关重要.
研究的目的:
- 调查与瑞典本土人相比,第一代和第二代移民中复发性骨质疏松性骨折的风险.
主要方法:
- 一项全国性的公开队列研究包括超过296,000名年龄在50岁以上,先前有骨折的个人.
- 移民被归类为第一代或第二代.
- 骨质疏松性骨折 (部,部,前臂,脊椎,骨盆) 在2010-2018年期间通过国家患者登记册确定.
- 根据年龄,并发症和社会人口统计状况调整后的后勤回归分析.
主要成果:
- 第一代移民男性的风险降低了10% (或0.90),第二代移民男性的风险降低了15% (或0.85),第二次骨质疏松性骨折的风险.
- 与瑞典本土女性相比,第一代移民女性的风险类似 (OR 0.95),第二代移民女性的风险相同 (OR 1.00).
- 来自亚洲的男性,来自东欧,波罗的海国家,亚洲和拉丁美洲的女性,来自北欧国家的父母的男性的风险明显较低.
结论:
- 第一代和第二代移民男性出现稍微降低后续骨质疏松性骨折的风险.
- 在移民妇女和瑞典本土人之间,复发性骨质疏松性骨折的风险是可比的.
- 骨折风险的区域差异凸显了对移民健康的细微方法的需要.
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