在TAVR患者中的巴特尔指数 - - 一个新的使用旧得分
Magda Haum1,2, Lukas Weyde3, Julius Steffen3,4
1Medizinische Klinik Und Poliklinik I, Klinikum Der Universität München, LMU München, LMU Klinikum, Marchioninistr. 15, Munich, 81377, Germany. Magda.haum@med.uni-muenchen.de.
概括
巴特尔指数 (BI) 可以预测通过导管大动脉置换 (TAVR) 进行大动脉狭窄后的长期存活率. 较低的BI分数表明脆弱性,并且与TAVR后的生存率显著降低有关.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 干预心脏病学 干预心脏病学
背景情况:
- 过导管大动脉置换 (TAVR) 是对大动脉狭窄症 (AS) 的标准治疗方法.
- 精确的患者选择对于优化老年TAVR患者长期结果至关重要.
- 巴特尔指数 (BI) 评估日常生活活动和功能状态.
研究的目的:
- 评估巴特尔指数 (BI) 在TAVR后长期存活的预后价值.
- 确定BI是否可以识别可能从TAVR中受益较少的脆弱患者.
- 评估BI和STS分数对死亡率的综合预测能力.
主要方法:
- 一个单一中心对475名接受TAVR治疗的患者进行了回顾性分析,以治疗严重症状的AS.
- 根据BI分数,患者被分为两组:较高的BI (≥90) 和较低的BI (<90).
- 两组之间的长期存活率进行了比较,并分析了BI和STS死亡率得分的预测准确性.
主要成果:
- 较低BI分数的患者年龄较大,手术风险较高 (STS分数),功能较差.
- 在4年后的长期存活率在较低的BI组 (53.1%) 与较高的BI组 (80.0%) 相比显着较低.
- 与单独的STS得分相比,将STS得分与BI得分结合起来可以改善死亡率预测 (C指数为0.683比0.626).
结论:
- 巴特尔指数 (BI) 是大动脉狭窄症TAVR后长期生存的强有力的预测指标.
- BI有效地识别了在手术后的前四年内具有较高死亡风险的脆弱患者.
- 应考虑BI作为严重AS患者TAVR前评估的一部分.
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