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Updated: Feb 19, 2026

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在慢性阻塞性睡眠呼吸暂停的老鼠模型中,JAK1-STAT1信号通路触发了炎症反应

Lin Yang1, Jie He2

  • 1Department of Pulmonary and Critical Care Medicine, Huili People's Hospital, Liangshan Yi Autonomous Prefecture, Huili, Sichuan, China.

PloS one
|February 17, 2026
PubMed
概括

在阻塞性睡眠呼吸暂停 (OSA) 中,慢性间歇性缺氧 (CIH) 激活了JAK1-STAT1通路,导致炎症. 抑制JAK1降低了炎症并改善了呼吸道功能,这表明OSA的治疗点.

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