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儿科偶发性前庭神经瘤的独特特征
Udi Shapira1, Riana Kipiani Abdul Halim2, Jeong Geum Lee3
1Department of Otorhinolaryngology, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, Republic of Korea; Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Medical Center, Tel Aviv, Israel; The School of Medicine, Tel-Aviv University, Tel Aviv, Israel.
American journal of otolaryngology
|February 17, 2026
概括
儿科偶发性前庭神经瘤 (VS) 的复发率明显高于成人VS. 较年轻的儿童,特别是14岁以下的儿童,面临着较差的结果,这表明需要更积极的监测和治疗策略.
科学领域:
- 神经瘤学神经瘤学
- 儿科神经外科 儿科神经外科
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 静脉神经瘤 (VS) 是一种罕见的瘤,通常影响成年人.
- 儿童中偶发性VS较少见,其特征需要进一步调查.
- 了解儿科VS结果对于定制治疗策略至关重要.
研究的目的:
- 为了比较儿科和成人间歇性前庭神经瘤 (VS) 之间的瘤控制结果.
- 为了确定儿科VS队列中瘤复发的年龄相关差异.
- 为儿童VS的治疗和监测方法提供信息.
主要方法:
- 追溯匹配病例控制研究,比较儿科 (≤21岁) 和成人 (>21岁) 患者的零星单边VS.
- 根据瘤大小和位置,患者与1:2匹配.
- 主要结局是瘤控制,定义为稳定的疾病与需要治疗的复发/再生.
主要成果:
- 9名儿科患者与18名成年人进行了对照;基线特征相似.
- 瘤复发/复发发生在44%的儿科患者和6%的成年人中 (P=0.005).
- 小儿科队列中较年轻的儿童 (<14岁) 与较年长的儿童相比,复发率更高.
结论:
- 与成人VS相比,儿科零星VS的瘤控制明显较差,即使与大小和位置相匹配.
- 年龄较小的儿童 (<14岁) 特别容易在手术后出现瘤复发.
- 研究结果表明,对于儿科VS患者来说,可能需要更积极的治疗和监测策略.
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