在学龄非常早的儿童中休息状态网络:与认知和思想理论的联系
Marta Elena Carrasco-Solís1,2, Sofia Amaoui3, Carolina Laynez-Rubio1,2
1Department of Pediatrics, School of Medicine, University of Granada. Granada, Spain.
Social cognitive and affective neuroscience
|February 17, 2026
概括
妊娠年龄 (GA) 影响非常早产儿的大脑连接. 某些网络中的更高连接性与更好的认知和思维理论 (ToM) 技能相关,这表明潜在的干预目标.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 儿科成像学 儿科成像学
背景情况:
- 非常早产 (<32周GA) 可以影响神经发育.
- 这些儿童的休息状态功能连接 (rsFC) 模式可能会发生变化.
- 了解这些变化对于识别认知和社会认知缺陷至关重要.
研究的目的:
- 为了检查怀孕年龄 (GA) 和rsFC在学龄非常早产儿童之间的关系.
- 调查这些神经连接模式如何与认知和思维理论 (ToM) 的表现有关.
主要方法:
- 休息状态fMRI数据从52名非常早产儿 (GA <32周) 中获得.
- 使用独立组件分析 (ICA) 来提取静止状态网络.
- 进行了认知和ToM评估.
主要成果:
- 在左后大脑网络 (lpCER) 中,GA与rsFC正相关,与前置默认模式网络 (aDMN) 和右前侧双网络 (rFPN) 负相关.
- 增加的lpCER连接性与更好的语言理解,视觉空间能力,流动推理,工作记忆和ToM有关.
- 增加的aDMN连接与较低的工作记忆相关,并且减少的rFPN连接与较低的IQ相关.
结论:
- 妊娠年龄显著影响非常早产儿的内在大脑网络连接.
- 特定的rsFC模式与认知和社会认知结果有关.
- 这些发现突出了在早产人口中针对性干预的潜在神经标志物.
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