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Updated: Feb 19, 2026

Substrate Generation for Endonucleases of CRISPR/Cas Systems
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Published on: September 8, 2012

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在II-A型CRISPR-Cas系统中采用Cas9定向间隔器的结构基础

Zhaoxing Li1, Yutao Li2, Jianping Kong2

  • 1State Key Laboratory of Natural Medicines, School of Pharmacy, China Pharmaceutical University, Nanjing, China; Chongqing Innovation Institute, China Pharmaceutical University, Chongqing 401135, China; Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore 117543, Singapore.

Molecular cell
|February 17, 2026
PubMed
概括

CRISPR-Cas9系统使用Cas9,Csn2和Cas1-Cas2来获取外来DNA. Cryo-EM揭示了这些蛋白质如何识别DNA,并确保精确整合原生细胞免疫力.

关键词:
克里斯普尔是什么意思?克里斯普尔是什么意思?这就是Cas1的情况.这就是Cas9的情况.收购空间空间 收购空间

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