内血管血栓切除术后的生活质量:一个多中心,前性,观察性研究
Rahul R Karamchandani1, Hongmei Yang2, Liang Wang2
1Department of Neurology, Neurosciences Institute, Wake Forest University School of Medicine, Atrium Health, 1000 Blythe Blvd, Charlotte, NC 28203, United States.
概括
生活质量 (QOL) 测量为内血管血栓切除 (EVT) 患者提供了超越传统尺度的宝贵见解. 这些患者报告的结果与功能恢复有显著的相关性,有助于全面评估中风护理.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 医疗成像医学成像
背景情况:
- 与健康相关的生活质量 (QOL) 度量越来越被认可,但在临床实践中未得到充分利用.
- 传统的天平可能无法完全捕捉中风后的患者体验.
- 这项研究调查了内血管血栓切除术 (EVT) 患者队列中的QOL.
研究的目的:
- 在接受内血管血栓切除术 (EVT) 的个体中评估患者报告的生活质量 (QOL).
- 确定质量生活指标与EVT后的功能结果 (mRS) 之间的相关性.
- 为了确定与EVT患者的QOL结果相关的因素.
主要方法:
- 一项多中心,前性,观察性研究,涉及212名EVT患者.
- 主要结果:90天的EuroQol5维5级 (EQ-5D-5L) 指数. 二次结果:视觉模拟尺度 (VAS).
- 使用斯皮尔曼相关性和线性回归分析来评估QOL,mRS和其他临床因素之间的关系.
主要成果:
- 平均EQ-5D-5L指数为0.45±0.42,中位数VAS为75. 这一指数为0.45±0.42.
- 超过40%的受试者在个别领域报告了QOL问题,近80%的人在至少一个领域报告了问题.
- EQ-5D-5L和VAS与90天的mRS显示出强烈的相关性 (rs = -0.912和rs = -0.709,分别). 患病前的mRS,脑血量指数和停留时间与QOL有关.
结论:
- 九十天的QOL测量为EVT患者的修改Rankin尺度 (mRS) 提供了有价值的附加信息.
- 患者报告的结果捕捉了康复的关键方面,这些方面并不总是仅仅反映在功能评分上.
- 整合QOL评估可以提高对中风治疗有效性的综合评估.
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