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Updated: Feb 19, 2026

Capillary Electrophoresis Separation of Monoclonal Antibody Isoforms Using a Neutral Capillary
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干扰和故障:高度IgM单克隆蛋白在毛细血管区域电泳中的挑战

Yanhua Zhao1, Minjie Zhang1, Wei Gan1

  • 1Department of Laboratory Medicine, West China Hospital, Sichuan University, Sichuan Clinical Research Center for Laboratory Medicine, and Clinical Laboratory Medicine Research Center of West China Hospital, Chengdu 610041, Sichuan Province, China.

Clinical biochemistry
|February 17, 2026
PubMed
概括

沃尔登斯特罗姆巨球蛋白血症中的高IgM水平可能导致毛细血管区域电泳 (CZE) 失败. 贝塔-默卡波乙醇 (BME) 预处理成功解决了干扰,防止了假阴性结果,并确保了准确的诊断.

关键词:
毛细管区电泳发生在毛细管区.克里奥格洛布林 (Cryoglobulin) 是一种球蛋白.有一个假负的结果.这是一种IgM单克隆性胃病变.这是一种β-mercaptoethanol.

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