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Updated: Jul 10, 2026

Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein
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通过蛋白质放大方法诊断同核蛋白病变:方法学和文献分析分析

Alexander A Groshkov1, Nataliya A Kolotyeva2, Pavel P Tregub2,3

  • 1Russian Center of Neurology and Neurosciences, Moscow, 125367, Russia. alexander.groshkov@mail.ru.

Biochemistry. Biokhimiia
|February 17, 2026
PubMed
概括

像RT-QuIC这样的蛋白质放大方法,通过检测粉样蛋白聚合物,显示出早期神经退行性疾病诊断的前景. 尽管面临挑战,这些技术为同核蛋白病变提供了可访问和标准化的方法.

关键词:
这就是PMCA.帕金森病是帕金森氏症的一种疾病.美国人,美国人.文献计量分析的分析大脑脊髓液中的脑脊液.患有利维体痴呆症的痴呆症早期诊断 早期诊断 早期诊断纤维化的纤维化多个系统缩.神经退行性疾病的神经退行性疾病蛋白质放大 蛋白质放大有关同核蛋白病变的疾病.α-synuclein 是一种同核蛋白.

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