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Updated: Feb 19, 2026

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
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作为释放ibuprofen-copovidone无形固体分散的失败机制,结合是一种失败机制

Michelle L Cousineau1, Alexandru Deac1, Hitesh S Purohit2,3

  • 1Department of Industrial and Molecular Pharmaceutics, College of Pharmacy, West Lafayette, Indiana 47907, United States.

Molecular pharmaceutics
|February 17, 2026
PubMed
概括

在无形固体分散 (ASD) 中的药物聚合物结可以在高药物负载下导致药物释放不良. 这项研究揭示了这种相互作用如何导致相位分离,影响药物的生物可用性和配方设计.

关键词:
无形固体分散的无形固体分散通过联结,形成联结.阶段分离的阶段分离.释放 释放 释放 释放 释放

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