对错觉的情绪导向认知行为治疗 (CBTd-E) 的有效性,与单盲随机对照试验中的等待名单相比
Stephanie Mehl1,2, Christopher Hautmann3, Björn Schlier4,5
1Marburg University, Department of Psychiatry and Psychotherapy, Marburg, Germany. Stephanie.mehl@staff.uni-marburg.de.
Schizophrenia (Heidelberg, Germany)
|February 17, 2026
概括
一种以情绪为导向的错觉认知行为疗法 (CBTd-E) 并没有显著减少精神病患者的错觉. 虽然CBTd-E改善了一般的精神病理学和像情绪调节这样的目标机制,但它没有影响妄想严重性的首要结果.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 认知行为疗法是认知行为疗法.
背景情况:
- 精神疾病中的妄想是一个重大的临床挑战.
- 针对所谓的因果因素,如影响调节和不适应性模式,可能会增强心理干预.
- 为了解决这些因素,开发了一种以情感为导向的错觉认知行为疗法 (CBTd-E).
研究的目的:
- 评估CBTd-E在减少精神病患者妄想的疗效.
- 评估CBTd-E对拟议的目标机制的影响,包括影响法规和不适应方案.
- 检查CBTd-E对二次结果的影响,如一般精神病理学,积极和消极症状,抑郁和功能.
主要方法:
- 一个单盲,多中心,随机,等候名单控制的试验在三个德国门诊诊所进行.
- 94名患有精神疾病和持续妄想的患者被随机分配到6个月内接受25个单独的CBTd-E疗程或等候名单对照.
- 评估是在基线,3个月和6个月进行的,使用包括精神病症状评分表 (PSRS) 妄想子表在内的措施.
主要成果:
- CBTd-E对主要结果 (PSRS妄想分级;d = -0.45) 没有显著的好处.
- 在一般精神病理学 (d = -0.56) 中观察到有利于CBTd-E的显著效应,但在积极/消极症状,抑郁症或功能方面没有.
- 在提出的目标机制中注意到了改善:认知重新评估 (d = 0.59),担忧 (d = -0.52),睡眠质量 (d = -0.49) 和自尊 (d = 0.36).
结论:
- 尽管CBTd-E对目标机制和一般精神病理学产生了积极的影响,但CBTd-E并没有在减少妄想方面表现出有效性.
- 这些发现表明,虽然以情感为中心的CBT可能会影响相关的心理过程,但它对妄想严重性的直接影响需要进一步调查.
- 个性化模块化干预可能是一个潜在的策略,以增强治疗对错觉的影响.
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