益生菌,益生菌和后生菌治疗:一个系统的审查
Peyton V Warp1,2, Sophie M Bilik2, Lina M Ferrari2
1Dr Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1600 NW 10th Ave, Miami, FL, 33136, USA.
Dermatology and therapy
|February 17, 2026
概括
微生物组调节疗法,如益生菌,益生菌和后生菌,显示出对管理的承诺. 这些治疗方法是安全的,可以减少病变,而益生菌目前拥有最强有力的证据基础.
科学领域:
- 皮肤病学 皮肤病学
- 微生物学 微生物学
- 药理学 药理学是指药理学的学科.
背景情况:
- 的管理正在探索微生物组调节疗法.
- 益生菌,益生菌和后生菌针对肠-皮肤轴,炎症和屏障功能.
- 这些疗法被研究为常规治疗的辅助或替代方案.
研究的目的:
- 系统地审查口服和局部益生菌,益生菌和后生菌对的安全性和有效性.
- 为了描述这些微生物组调节剂的当前证据基础.
主要方法:
- 一个PRISMA引导的随机对照试验,队列研究和病例控制研究的系统审查.
- 搜索了PubMed,Embase,Web of Science和Cochrane数据库,从创立到2025年8月.
- 包括报告口服/局部益生菌,益生菌和后生菌在患者的安全性和/或疗效的研究.
主要成果:
- 包括33项涉及2112名患者的研究;治疗持续时间从4-25周不等.
- 所有方法都显示出良好的安全性,没有严重的不良事件.
- 聚合的平均损伤减少:前生物 -37.2%,益生菌 -45.2%,后生物 -49.5%与对照组的 -37%相比.
结论:
- 益生菌,益生菌和后生菌疗法对于减少病变是安全有效的.
- 这些药物可以提高耐受性和有效性,当与标准治疗相结合时.
- 益生菌有最强有力的证据,而前生物和后生物有希望;需要进一步的研究.
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
936
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
936
Surface Membrane Barriers
3.0K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
3.0K


