左心室表皮脂肪组织与在肺静脉隔离期间持续的AF终止相关
Bowen Qiu1,2, Jianfan Shen2, Lei Chen2,3
1Department of Cardiology, Qingdao Eighth People's Hospital, Qingdao, China.
Pacing and clinical electrophysiology : PACE
|February 18, 2026
概括
左心房上心脏脂肪组织 (LA-EAT) 与射频导管切除期间持续性心房动 (PersAF) 的终止独立相关. 较低的LA-EAT体积预测了成功的终止,改善了切除结果.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 电子生理学 电子生理学
背景情况:
- 持续性心房动 (PersAF) 管理依赖于成功的射频导管切除 (RFCA).
- 心脂肪组织 (EAT) 影响心房动 (AF) 的维持.
- 在RFCA期间EAT对PersAF终止的影响仍然未经调查.
研究的目的:
- 调查左心房EAT (LA-EAT) 与肺静脉隔离 (PVI) 期间PersAF终止之间的关联.
主要方法:
- 对203名第一次接受RFCA的PersAF患者进行了回顾性观察性研究.
- 通过计算机断层扫描血管学 (CTA) 测量左心房EAT体积.
- 终止被定义为在PVI期间转换为鼻节律或稳定的心房/心跳动.
主要成果:
- LA-EAT体积,AF持续时间和心力衰竭是PersAF终止的独立预测因素.
- 一个包含LA-EAT的模型证明了终结的预测准确度有所提高.
- 整合LA-EAT显著增强了歧视和重新分类的终止预测.
结论:
- 左心房EAT是PVI期间PersAF终止的独立预测因子.
- LA-EAT的体积是成功实现废弃结果的重要因素.
- 进一步研究EAT在AF剥离中的作用是有必要的.
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