相关实验视频

Updated: Feb 19, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

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关于瘤突变负担的检测和临床应用的专家共识

Zhenying Guo1, Chunwei Xu2, Shirong Zhang3

  • 1Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou 310014, China.

Cancer biology & medicine
|February 18, 2026
PubMed
概括

瘤突变负担 (TMB) 在预测免疫治疗反应方面表现有前途,但缺乏标准化. 这一共识为TMB测试和在中国的临床应用提供了建议,以改善患者护理.

关键词:
生物标志物 生物标志物有针对性的面板测序.瘤免疫疗法 免疫疗法瘤突变负担的突变负担整体外因子测序的测序

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Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

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相关概念视频

Mismatch Repair01:20

Mismatch Repair

Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
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