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Updated: Feb 19, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
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作为IGF1R抑制剂的 styrylquinoline衍生物

Patryk Zioła1, Katarzyna Malarz1, Marcin Pacholczyk2

  • 1A. Chełkowski Institute of Physics, University of Silesia in Katowice, 75 Pułku Piechoty 1a, 41-500 Chorzów, Poland.

ACS medicinal chemistry letters
|February 18, 2026
PubMed
概括

styrylquinoline类似物显示出对质母细胞瘤的抗增殖作用. 这些化合物是胰岛素类生长因子1受体氨酸激酶的强有力的抑制剂,表明治疗潜力.

关键词:
IGF1R 抑制剂的使用它们具有抗增殖活动的抗增殖活性.质母细胞瘤多形这种基诺林 (styrylquinoline) 是一种基诺林.

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