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同时服用内化RGD可增强肝细胞癌的抗PD-L1疗法

Jan Henrik Klug1, Blerina Aliraj2, Lucia Alcober-Boquet1

  • 1Goethe University Frankfurt, University Hospital, Medical Clinic 1, Frankfurt am Main, Germany.

JHEP reports : innovation in hepatology
|February 18, 2026
PubMed
概括

与抗PD-L1疗法同时使用iRGD可通过改善药物输送和减少瘤免疫抑制,显著提高肝细胞癌 (HCC) 鼠标模型的治疗效果. 这种方法有望改善HCC患者的免疫检查点抑制剂 (ICI) 反应.

关键词:
组合疗法是一种联合疗法.药物运输 药物运输 药物运输肝细胞癌是肝细胞癌.免疫检查点抑制剂 免疫检查点抑制剂免疫治疗是一种免疫疗法.瘤微环境是一个微环境.

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