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第一种类型的干扰素依赖性和干扰素独立性信号是鼠狼模型中自身抗体生产的基础

Jerrold S Levine1,2, Céleste Pilon3,4, Rebecca Subang3,4

  • 1Section of Nephrology, Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA.

Journal of translational autoimmunity
|February 18, 2026
PubMed
概括

系统性红斑狼 (SLE) 的启动涉及TRIF-依赖的途径,影响自身抗体的产生. 树突细胞和巨细胞中的I型干扰素 (IFN-I) 依赖基因和独立基因都在SLE病变发生过程中至关重要.

关键词:
自动抗体是一种自身抗体.自动抗原是一种自动抗原.鼠模型的模型.在RNA-Seqq.系统性红血性狼 (Systemic lupus erythematosusus) 是一种全身性狼.β2-糖蛋白 I 是一种β2-糖蛋白.

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