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Updated: Jun 28, 2026

Experimental Demyelination and Remyelination of Murine Spinal Cord by Focal Injection of Lysolecithin
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Published on: March 26, 2015

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由于Aurkb的缺乏,破坏了微质的发育,平衡,并阻碍了 cuprizone 诱导的脱后的再化

Weixing Yan1,2, Dong Xiang3, Li Du1,2,4

  • 1Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogen Biology and Immunology, School of Basic Medical Science, Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.

iScience
|February 18, 2026
PubMed
概括

极光B激酶 (Aurkb) 对于微质功能在复髓化和神经健康方面至关重要. 它的缺失会损害髓碎片的清除,阻碍衰老和多发性硬化症 (MS) 的修复.

关键词:
细胞生物学 细胞生物学神经科学是一个神经科学.

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Mismatch Repair01:36

Mismatch Repair

Overview
Restarting Stalled Replication Forks02:37

Restarting Stalled Replication Forks

DNA replication is initiated at sites containing predefined DNA sequences known as origins of replication. DNA is unwound at these sites by the minichromosome maintenance (MCM) helicase and other factors such as Cdc45 and the associated GINS complex.The unwound single strands are protected by replication protein A (RPA) until DNA polymerase starts synthesizing DNA at the 5’ end of the strand in the same direction as the replication fork. To prevent the replication fork from falling apart, a...
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Separation of Sister Chromatids

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At the onset of anaphase, separase, a proteolytic enzyme, is...
Anaphase Promoting Complex00:50

Anaphase Promoting Complex

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Drugs that Destabilize Microtubules

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Mismatch Repair01:20

Mismatch Repair

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