加密腺体上囊核心结果测量集 (AFCOMS):标准化定义和测量仪器
Nedim Tabakovic1,2, Shivani Joshi3, Merel Kimman4
1Department of Surgery and Colorectal Surgery, Maastricht University Medical Centre+, the Netherlands.
EClinicalMedicine
|February 18, 2026
概括
一个新的核心结果测量集 (COMS) 对尾研究标准化结果定义和测量工具. 这提高了对密码腺体尾研究的一致性和证据综合.
科学领域:
- 胃肠病学 胃肠病学
- 手术研究的研究.
- 患者报告的结果
背景情况:
- 密码腺门囊显著影响患者的生活质量.
- 现有的囊核心结果集 (AFCOS) 缺乏标准化的结果定义和测量工具,阻碍了研究的可比性.
- 需要与AFCOS一致的核心成果测量集 (COMS),以改善未来的证据综合.
研究的目的:
- 建立一个国际,共识驱动的核心成果测量集 (COMS) 对于密码腺尾研究.
- 为了使COMS与现有的道核核心结果集 (AFCOS) 保持一致.
- 为了提高研究的一致性,标准化结果定义和测量工具.
主要方法:
- 一项按照COMET方法的三阶段研究.
- 第一个阶段:对AFCOS结果定义和工具的范围审查. 第二阶段:使用COSMIN标准对心理特征的评估. 第三阶段:国际两轮德尔菲调查和与患者和医疗保健专业人员的共识会议.
- 在定义,测量仪器 (门质量生活量表,Vaizey评分,数值评分表) 和时间点 (3个月和12个月) 上达成共识.
主要成果:
- 达成国际共识,对临床和放射性治,复发,新发育,并发症 (Clavien-Dindo) 和重新干预的标准化定义达成国际共识.
- 选择的仪器包括囊质量生活量表,Vaizey评分,以及患者满意度的数值评分表.
- 治疗后3个月和12个月为评估结果的标准时间点.
结论:
- 开发的AFCOMS为密码腺 Anal fistula研究提供了标准化的定义和测量工具.
- 实施AFCOMS将提高跨研究报告的一致性.
- 这种标准化将有助于在囊研究中进行强有力的证据综合.
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