在APOA5 c.553G中可逆降低的脂蛋白脂酶>T相关的过高甘油三血症成功地用pemafibrate治疗

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Updated: Feb 20, 2026

Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation
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Published on: January 28, 2021

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Shozo Miyauchi1, Yuji Utsunomiya1, Masashi Okamoto1

  • 1Department of Diabetes and Endocrinology, Ehime Prefectural Central Hospital, Matsuyama, Ehime, Japan.

Endocrinology, diabetes & metabolism case reports
|February 18, 2026
PubMed
概括

一种罕见的同卵性APOA5突变导致严重的高甘油三血症,对生活方式的改变没有反应. 纤维酸治疗使甘油三水平正常化,改善了脂蛋白脂酶功能,证明了其在遗传性高甘油三血症中的有效性.

关键词:
脂蛋白 A-V 脂蛋白 A-V 是一种超米克隆血症 (hyperchylomicronemia) 是一种疾病,过高甘油三糖血症的发生.脂蛋白脂酶是一种脂蛋白脂酶.纤维化 纤维化

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