非白发性Pomeranians和白发性X的毛皮类型之间的组织学和三图学差异
Ilse van Hensbergen1, Chiara Brachelente2, Jaco van der Lugt3
1IVC Evidensia Referral Hospital EDZ Arnhem, Arnhem, the Netherlands.
Veterinary dermatology
|February 18, 2026
概括
波默兰犬的脱发症X (AX) 与特定的外套类型有关. 组织学和三色学分析揭示了AX,羊毛和闪亮的外套之间的毛囊和脆弱性的明显差异.
科学领域:
- 兽医皮肤病学 兽医皮肤病学
- 狗类组织病理学
- 三学是指三学的学科.
背景情况:
- 脱毛X (AX) 是波美伦犬中普遍存在的疾病.
- 皮肤组织学有助于AX诊断.
- 波默兰犬的羊毛外套类型可能表明AX的风险更高.
研究的目的:
- 为了比较皮肤组织学和皮肤三图学发现,在Pomeranians与白发症X (AX).
- 为了区分受AX影响的Pomeranians和不受影响的羊毛 (W) 或闪亮 (S) 毛皮类型的Pomeranians.
主要方法:
- 研究了72只Pomeranian:30只有AX,22只有羊毛外套,20只有闪亮的外套.
- 皮肤活检经历了组织学分析.
- 毛发样本被评估使用三重图和扫描电子显微镜 (SEM).
- 毛囊数量,头发类型,异原毛囊和头发脆弱性被统计评估.
主要成果:
- 与羊毛和闪亮的涂层狗 (5.1) 相比,患有AX的Pomeranians每组的毛囊较少 (4.1).
- 在AX狗 (85.3) 中,毛发的脆弱性明显高于羊毛 (53.6) 和闪亮 (26.3) 涂层的狗.
- 与闪亮的狗相比,在AX和羊毛的狗中,trichorrhexis nodosa比率较高.
结论:
- 组织学和三色学分析显示,波默兰人之间外套类型的明显差异.
- 这些发现对于在Pomeranians中准确诊断Alopecia X至关重要.
- 毛皮类型的特征应与诊断AX的临床症状一起考虑.
关键词:
脱发症 X 脱发症 X 脱发症毛囊群的毛囊群是什么?毛囊群的毛囊群是什么发型周期停止 发型周期停止拔发 拔发 拔发 拔发 拔发 拔发皮肤活检皮肤活检三雷克西斯 (Trichorrhexis) 诺多萨 (Nodosa) 是一种三雷克西斯.羊毛外套是一种羊毛外套.更多相关视频
13:58Flat Mount Imaging of Mouse Skin and Its Application to the Analysis of Hair Follicle Patterning and Sensory Axon Morphology
Published on: June 25, 2014
22.5K
08:09CUBIC Protocol Visualizes Protein Expression at Single Cell Resolution in Whole Mount Skin Preparations
Published on: August 4, 2016
12.2K
相关概念视频
Accessory Structures of the Skin: Hair Growth and Types
2.6K
Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
2.6K
Accessory Structures of the Skin: Hair and Hair Follicles
4.8K
Hair and hair follicles are integral components of the integumentary system. Hair is a filamentous structure composed mainly of a protein called keratin. It is found on the surface of the skin throughout the body, except for areas such as the palms of the hands and soles of the feet.
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinized cells. Hair strands originate at the epidermal penetration called the hair follicle. The hair shaft is the part...
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinized cells. Hair strands originate at the epidermal penetration called the hair follicle. The hair shaft is the part...
4.8K
Epistasis
50.5K
In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
50.5K
