自闭症青少年中便秘的高负担 - 一个由PCORnet®支持的全国性查询
Bruno P Chumpitazi1,2, Allison Zelinski3, Nicole Marchesani3
1Department of Pediatrics, Duke University School of Medicine, Durham, NC USA.
The American journal of gastroenterology
|February 18, 2026
概括
大约22%的自闭症儿童经历便秘,这是非自闭症青少年的两倍多. 这种情况导致腹部疼痛增加和自闭症患者更高的医疗保健使用率.
科学领域:
- 儿科健康 儿科健康
- 胃肠病学 胃肠病学
- 神经发育障碍 神经发育障碍
背景情况:
- 胃肠道 (GI) 问题经常在患有自闭症谱系障碍 (ASD) 的儿童中观察到.
- 目前关于自闭症青少年便秘和相关医疗保健需求的数据是有限的.
- 了解这些问题对于改善对自闭症儿童的照顾至关重要.
研究的目的:
- 为了确定被诊断为自闭症的儿童中便秘的流行率.
- 评估医疗保健利用模式,包括急诊室 (ED) 访问和住院治疗,用于自闭症儿童的便秘.
- 将这些结果与非自闭症儿童进行比较.
主要方法:
- 在70个卫生系统 (2015-2024) 中,利用了超过2000万年龄在6-17岁的人员的电子健康记录.
- 确定了自闭症和非自闭症儿童的队列,并诊断了便秘病例.
- 分析了关于腹痛诊断,急救诊所和住院住院的数据.
主要成果:
- 在22%的自闭症儿童中诊断出便秘,而非自闭症儿童中这一比例为9%.
- 患有便秘的自闭症儿童报告了更高的腹痛率 (34%vs8%).
- 与没有便秘的儿童相比,患有便秘的自闭症儿童因腹部疼痛/便秘住院的次数 (26%对3%) 和住院的次数 (16%对1%) 显著增加.
结论:
- 几乎五分之一的自闭症儿童患有便秘.
- 患有便秘的自闭症儿童在不规划的医疗保健利用率上显著提高.
- 这些发现凸显了针对性干预和改善自闭症患者便秘管理的需要.
相关概念视频
01:21Drugs for Treatment of Constipation-Predominant IBS
926
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
926
01:19Autism Spectrum Disorder
1.3K
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
1.3K
01:17Chronic Bowel Disorders: Introduction
823
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
823
01:25Assessment of the Rectum and Anus
1.4K
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
1.4K
01:30Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
962
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
962
01:29Assessment of the Gastrointestinal System II: Health Perception Pattern
526
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
526