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基于地区人口的PSA信息和测试计划的五年结果
Henrik Ugge1,2, Georgios Daouacher2,3, Mauritz Waldén3
1Department of Urology, Faculty of Medicine and Health, Örebro University Hospital, Örebro, Sweden.
BJU international
|February 18, 2026
概括
瑞典的一个区域邮寄前列腺特异性抗原 (PSA) 测试计划取得了高出席率,增加了PSA测试和前列腺癌诊断,特别是低风险瘤. 谨慎的查策略至关重要,以防止过度检测.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 公共卫生 公共卫生
- 在瘤学瘤学.
背景情况:
- 使用前列腺特异性抗原 (PSA) 测试对前列腺癌进行基于人口的查是一个争论的话题.
- 区域实施PSA测试计划需要对吸收和结果进行评估.
研究的目的:
- 描述一个区域邮寄的PSA信息和测试计划在最初的五年中的结果.
- 评估PSA检测率,诊断活动和癌症检测率.
主要方法:
- 一封关于PSA检测的邮寄信息信每五年发给瑞典Värmland的50-70岁的男性.
- 男人被指示联系PSA检测的初级保健;水平≥3μg/L导致泌尿器科转诊.
- 地方和国家注册表被用来跟踪测试,诊断和癌症发病率.
主要成果:
- 大约20%的知情男性在六个月内接受了PSA测试,随着时间的推移,吸收率会增加.
- 在接受测试的男性中,3.5%的PSA≥3μg/L,1.5%进行了活检,0.8%被诊断为前列腺癌.
- 每年前列腺癌发病率增加,主要是在低风险和中等风险瘤中,并观察到高出席率.
结论:
- 一个邮寄的PSA信息和测试计划在斯堪的纳维亚地区是可行的,可以实现高参与率.
- 低风险瘤检测的增加需要谨慎,并强调需要强大的查策略和诊断算法,以防止过度诊断.
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