在治疗耐药和复发性三角神经疼痛中的部分感官根茎切除 - - 一个单一的中心体验经验
Ina Lange1, Ehab El Refaee2,3, Marc Matthes2
1Department of Neurosurgery, University Medicine Greifswald, Greifswald, Germany. Ina.Lange@med.uni-greifswald.de.
Acta neurochirurgica
|February 18, 2026
概括
部分感官根茎切除 (PSR) 提供了显著的疼痛缓解耐火性三角神经疼痛 (TN). 大多数患者立即感到疼痛减轻,长期持续受益,尽管感官变化是不可预测的.
科学领域:
- 神经外科 神经外科
- 神经学 神经学
- 疼痛管理 疼痛管理
背景情况:
- 部分感官根茎切除术 (PSR) 是治疗不耐治疗的三角神经疼痛 (TN) 的最后手段.
- 它被认为是对微血管减压或其他干预不响应的患者.
- 本研究详细介绍了作者对PSR的经验.
研究的目的:
- 评价部分感官树枝切除术 (PSR) 的疗效和结果,对患有难以治疗的三神经痛 (TN) 的患者.
- 评估长期缓解疼痛,患者满意度和与PSR相关的并发症率.
主要方法:
- 对接受PSR.患者的前性维护数据库的回顾性分析.
- 包括临床数据,MRI成像,手术视频和手术笔记.
- 为最后的后续评估进行的电话采访.
主要成果:
- 在2004年至2023年期间,48名患者接受了PSR,平均随访时间为38个月.
- 92.7%的患者 (44/48) 获得了立即的疼痛缓解.
- 从长期来看,72.1%的患者在没有药物治疗的情况下完全或部分缓解了疼痛,而23.3%的患者在减少药物治疗后感到满意.
结论:
- PSR显示了高患者满意度和耐火性TN的持续疼痛缓解.
- 这种手术可以是一个有价值的治疗选择,可以替代穿皮手术或放射性外科手术.
- 虽然有效,但PSR后感官缺陷的程度是不可预测的.
相关概念视频
Blood and Nerve Supply to the Bones
Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Psychosurgery
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...


