加拿大的AMR监测:2025年优先病原体清单的见解
Kahina Abdesselam1, Pia K Muchaal1, Aanchal Mishra1
1Antimicrobial Resistance Task Force, Public Health Agency of Canada, Ontario Canada.
PloS one
|February 18, 2026
概括
加拿大更新了2025年抗微生物耐药性 (AMR) 病原体清单,确定了像Candida auris.这样的新威胁. 监测系统取得了进展,但需要投资来弥补数据缺口,并解决高风险病原体的健康公平问题.
科学领域:
- 公共卫生 公共卫生
- 传染病流行病学 传染病流行病学
- 卫生监测 卫生监测
背景情况:
- 抗菌素耐药性 (AMR) 构成了全球健康的重大威胁.
- 加拿大2025年更新的AMR优先病原体清单反映了当前的耐药性趋势和监测进展.
- 此前在加拿大对抗药物耐药性的优先考虑发生在2015年.
研究的目的:
- 质量分析2025年AMR优先级结果.
- 评估加拿大AMR监测系统在检测高风险病原体方面的优势和局限性.
- 发现国家监管中的数据整合缺口.
主要方法:
- 使用多标准决策分析 (MCDA) 框架来确定病原体优先级.
- 根据包括健康公平在内的九个加权标准,评估了29种AMR病原体.
- 进行了对优先病原体监测系统覆盖范围的定性分析.
主要成果:
- 确定了Candida auris,耐药性淋病菌Neisseria gonorrhoeae和Mycoplasma genitalium作为新兴的高优先级威胁.
- 发现国家监测系统可能覆盖90%的优先病原体.
- 突出了缺乏常规诊断的病原体的持续监测差距,以及对边缘化人口的不成比例影响.
结论:
- 加拿大已经推进了综合和以公平信息为基础的AMR监测.
- 持续投资和合作对于解决数据缺口和改善公共卫生行动至关重要.
- 加强的国家系统整合了超过一半的优先病原体的实验室和流行病学数据.
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