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负面的社会关系作为加速衰老,炎症和多病症的新兴风险因素
Byungkyu Lee1, Gabriele Ciciurkaite2, Siyun Peng3
1Department of Sociology, New York University, NY 10003.
概括
负面的社会关系,或"麻烦者",加速生物衰老. 更多的麻烦者与更快的衰老和更差的健康状况有关,强调需要解决社会压力因素以实现更健康的衰老.
科学领域:
- 社会流行病学社会流行病学
- 生物衰老 生物衰老
- 表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.
背景情况:
- 负面的社会关系 ("骚扰者") 很常见,但研究不足.
- 它们可能会加速生物衰老,增加发病率.
- 了解它们的影响对于公共卫生至关重要.
研究的目的:
- 检查负面社会关系与加速生物衰老之间的关联.
- 为了调查与炎症和多病症的联系.
- 识别与接触麻烦者的人口和经验因素.
主要方法:
- 利用以自我为中心的网络数据和基于DNA甲基化的衰老时钟 (DunedinPACE,GrimAge2).
- 分析了来自印第安纳州一个州代表性的概率样本的唾液样本.
- 评估了与生物衰老,炎症和多病症相关的关联.
主要成果:
- 每个额外的麻烦都与约1.5%更快的衰老速度和约9个月更大的生物年龄相关联.
- 负面关系在弱势群体 (妇女,吸烟者,健康状况较差,童年不良经历) 中更为普遍.
- 亲戚和非亲戚骚扰者表现出有害影响,但配偶骚扰者没有.
结论:
- 负面的社会关系作为慢性压力因素,显著加速生物衰老.
- 需要减少有害社会暴露的干预措施,以促进更健康的衰老.
- 研究结果强调了社交网络构成对健康结果的重要性.
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