转移性前列腺癌患者的营养状况,睡眠质量和临床因素之间的关联
Digdem Dogan Akagunduz1, Hilal Sahin2, Engin Hendem3
1Department of Nutrition and Dietetics, Erzincan Binali Yildirim University Mengücek Gazi Training and Research Hospital, Erzincan, Turkey.
JCO oncology practice
|February 18, 2026
概括
营养不良和睡眠质量差在转移性前列腺癌 (mPC) 患者中很普遍. 通过营养查和干预来解决这些问题,可能会改善患者的福祉和生活质量.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 睡眠医学 睡眠医学
背景情况:
- 转移性前列腺癌 (mPC) 患者经常经历营养不良和睡眠质量差,这往往被忽视.
- 这些条件可以显著影响患者的结果和生活质量.
研究的目的:
- 为了研究营养状况,睡眠质量和患有mPC的男性的临床结果之间的关系.
- 在这个患者群体中确定与睡眠质量差相关的因素.
主要方法:
- 一项涉及91名患有第四期前列腺癌的男性的横截面研究.
- 使用主观全球评估 (SGA) 评估营养状况;使用匹兹堡睡眠质量指数 (PSQI) 评估睡眠质量.
- 分析了临床参数,实验室值 (白蛋白,血红蛋白,CRP) 和生活质量得分. 多变量逻辑回归确定了睡眠不足的预测因素.
主要成果:
- 65.9%的患者报告睡眠质量不佳,营养不良患者的患病率更高 (P < .001).
- 较差的营养状况与较低的白蛋白和血红蛋白,较高的CRP,较差的表现状况和生活质量的降低相关 (P < .001).
- 睡眠不足的独立预测因素包括CRP升高,血红蛋白降低和营养状况较差 (SGA C与A).
结论:
- 营养不良和全身炎症与睡眠质量受损和生活质量降低在mPC中密切相关.
- 营养查和有针对性的干预措施对于mPC患者的支持性护理至关重要.
- 优化营养状况和管理睡眠障碍可以提高患者的幸福感.
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