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强有力的补充查计划对假阴性率的影响:是时候制定新的基准吗?

Ashley Huppe¹, Onalisa Winblad¹, Jessica Peterson¹

¹Department of Radiology, University of Kansas Health System, Kansas City, KS, USA.

Journal of breast imaging

|February 18, 2026

概括

补充查 (SS) 在高风险患者中减少了症状间隔癌症 (ICs). 然而,许多高风险人群未充分利用SS MRI,错过了早期发现乳腺癌的机会.

科学领域:

放射学和医学成像学医学成像学
在瘤学瘤学.
公共卫生公共卫生

背景情况:

查乳房扫描假阴性率 (FNRs) 受间隔癌症 (ICs) 的影响,这些癌症可以通过补充查 (SS) 检测到.
了解SS对FNR的影响,并比较症状性IC与无症状假阴性 (FN) 癌症的特征,对于优化乳腺癌查方案至关重要.

研究的目的:

评估一个强大的SS计划对高于平均风险的患者的FNR的影响.
通过SS检测到的症状IC和无症状FN癌症之间的患者和瘤特征进行比较.

主要方法:

来自学术机构的查乳房造影审计指标的回顾性审查 (2018年7月-2023年6月).
假阴性 (FN) 癌症的识别,即在阴性查乳房镜检查后12个月内诊断出来的癌症.
分析患者的风险,检测方法,SS利用率和瘤特征,使用Cochran-Mantel-Haenszel和无变量测试.

主要成果:

在106,750次乳房影像中,发现了624种癌症和119种FN癌症 (FNR:1.11/1000).
具有症状的IC (45%) 在患有乳腺癌个人病史和更高风险 (74%) 的患者中更为频繁.
无症状的FN主要通过MRI检测 (60%),症状的IC在诊断时较大 (2.3厘米对1.5厘米).

结论:

一个强大的SS程序可以降低症状FNR低于国家基准.
患有症状性IC的高风险患者经常未充分利用SS MRI,这表明需要改善访问和意识.

关键词:

基准指标是指标中的基准值.乳房成像检查乳房成像检查一个错误的负面负面.查检查查检查查检查查检查补充查补充查

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