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醇诱导镇静对白质的影响 功能连接性

Jiayi Zhang1, Minyu Jian2, Leqing Zhou1

  • 1From the School of Artificial Intelligence, Beijing University of Posts and Telecommunications, Beijing, China.

Anesthesia and analgesia
|February 18, 2026
PubMed
概括

普罗波镇静剂显著减少白质的功能连接,影响关键的大脑网络. 这种干扰可能作为深度镇静状态的生物标志物.

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Parenteral Anesthetics: Overview01:24

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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
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