对不同类型的慢性鼻炎和欧斯塔基管功能障碍的相关性研究:流行率和风险因素的分析
Qihang Zhang1, Qianjin Zeng1, Jingtao Wang1
1Department of Otorhinolaryngology and Head and Neck Surgery, Zhengzhou University People's Hospital, Zhengzhou, China.
Clinics (Sao Paulo, Brazil)
|February 18, 2026
概括
欧斯塔基管功能障碍 (ETD) 的患病率在慢性鼻炎 (CRS) 亚型中是相似的,但血清IgE水平与慢性鼻炎与鼻息肉 (CRSwNP) 中的ETD症状相关. 无论ETDQ-7和ETS分数都有效地评估了CRS患者的欧斯塔基管功能.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 免疫学 免疫学 免疫学
背景情况:
- 慢性鼻炎 (CRS) 经常与尤斯塔希管功能障碍 (ETD) 一起存在.
- 了解不同CRS亚型中的ETD流行率和影响因素对于有效管理至关重要.
研究的目的:
- 调查ETD的患病率及其影响因素,慢性鼻炎 (CRS) 患者接受功能性内镜鼻手术 (FESS).
- 根据CRS的手术后遗传学亚型分析ETD患病率.
- 评估ETDQ-7和ETS评分在评估欧斯塔基管功能中的一致性和有效性.
主要方法:
- 92名接受FESS的CRS患者被分为没有鼻息肉的慢性鼻炎 (CRSsNP) 和带鼻息肉的慢性鼻炎 (CRSwNP) 组.
- CRSwNP组被进一步划分为一个带鼻多的异性慢性鼻炎 (EosCRSwNP) 子组.
- 收集的数据包括人口统计,成像,欧斯塔基管功能障碍问卷-7 (ETDQ-7) 和欧斯塔基管评分 (ETS).
主要成果:
- 在CRSsNP,CRSwNP和EosCRSwNP组中,ETD患病率没有显示出统计学上显著的差异.
- 在CRSwNP患者中,血清总IgE水平与ETDQ-7有中度的相关性,在EosCRSwNP患者中具有强烈的相关性.
- 在EosCRSwNP中,年龄和IgE被确定为ETD的独立风险因素. 在ETDQ-7和ETS分数之间的一致性在各个亚型之间有所不同,EosCRSwNP显示出最高的一致性.
结论:
- 在CRS亚型中,ETD的流行率是可比的.
- 血清总IgE是与CRSwNP中ETD症状相关的重要因素.
- 无论是ETDQ-7还是ETS得分都显示出在评估CRS患者欧斯塔基管功能时的良好的一致性和准确性.
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