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Updated: Feb 20, 2026

Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer
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Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer

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在结直肠癌中通过DNA甲基化介导的细胞外基因矩阵基因沉默

Otília Menyhart1, Dalma Müller1, Balázs Győrffy2

  • 1Cancer Biomarker Research Group, Institute of Molecular Life Sciences, Hungarian Research Network, Budapest, Hungary; Semmelweis University, Department of Bioinformatics, Budapest, Hungary.

Seminars in oncology
|February 18, 2026
PubMed
概括

DNA甲基化变化是结直肠癌 (CRC) 进展的关键. 我们的研究发现了细胞外矩阵 (ECM) 基因的高甲基化,为CRC提供了潜在的生物标志物和治疗点.

关键词:
在CRC中,CRC就是CRC.通过DNA甲基化.细胞外矩阵是一个细胞外矩阵.转移 转移 转移 转移瘤的进展情况.

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