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在心脏起器候选人中可能发生莱姆心炎与心房阻塞:来自塞尔维亚北部的初步结果

Dragana Gazibara¹, Verica Simin², Ivana Bogdan²

¹Medical Faculty of Novi Sad, University of Novi Sad, 21000 Novi Sad, Serbia; Department of Quality Control, Pasteur Institute Novi Sad, 21000 Novi Sad, Serbia.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

|February 18, 2026

概括

塞尔维亚约10%的起器候选人可能患有莱姆心脏病. 这表明莱姆氏病可能是流行地区心脏导电障碍的未被诊断的原因.

科学领域:

心脏病学心脏病学
传染性疾病传染性疾病
流行病学流行病学

背景情况:

需要心脏起器植入的心脏传导障碍在老年人群中很常见.
莱姆心炎是莱姆病的一种表现,可以导致显著的心脏导电异常.
莱姆心脏炎作为心脏起器植入的原因的患病率在塞尔维亚北部等特有地区尚未确立.

研究的目的:

确定患有新的心脏导电障碍,需要起器的患者中,可能出现莱姆心炎的血清学证据的比例.
评估在接受心脏起器植入的患者中针对导电异常进行莱姆病的血清学测试的有用性.

主要方法:

在塞尔维亚北部,注册了需要永久节奏的新传导障碍的成年人.
血清样本在基线和4周随访时采集,用于使用双层ELISA和免疫块算法进行抗BorreliaIgG测试.
可能的莱姆心炎是由血清转换或稳定/上升的IgG标位来定义的.

主要成果:

在完成随访的74名参与者中,8人 (10.8%) 显示了与可能的莱姆心炎相一致的血清学模式.
第三度心房静脉阻塞是最常见的导电障碍 (56.8%).
血清阳性患者年龄较大,男性在4周后观察到更高的IgG标位;最近没有报告咬或红血.

结论:

在这个流行地区,大约10%的鼓动器候选人可能患有莱姆心脏病.
在评估高度传导障碍时,利用莱姆病的配对血清学可以提高病因诊断和指导患者管理.

关键词:

在心房房阻塞.波雷莉亚的形虫 (Borrelia burgdorferi) 是一种形虫.莱姆心脏炎的病例之一.起器是一种心脏起器.血清测试血清测试血清测试

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