在婴儿期后的儿童中,大动脉门修复的长期结果
Michael Z L Zhu1, Igor E Konstantinov2, Tyson A Fricke1
1Department of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Australia; Department of Paediatrics, The University of Melbourne, Melbourne, Australia; Heart Research Group, Murdoch Children's Research Institute, Melbourne, Australia.
The Journal of thoracic and cardiovascular surgery
|February 18, 2026
概括
在婴儿期后的儿童中,大动脉 (AoV) 修复显示出良好的长期存活率. 最初的AoV修复使大多数儿童能够避免在成年之前更换假.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心脏外科手术 心脏外科手术
- 遗传性心脏病管理与管理
背景情况:
- 评估1岁以上儿童大动脉 (AoV) 修复的长期结果.
- 评估小儿病患者初级AoV修复的疗效.
研究的目的:
- 确定大动脉门修复在婴儿期后接受手术的儿童的长期结果.
- 确定影响AoV最初修复后需要重新操作或更换的因素.
主要方法:
- 对326名年龄≥1岁,接受初级AOV修复 (1980-2024) 的患者进行了回顾性研究.
- 分析早期和晚期死亡率,生存率,以及无需重新手术/更换的情况.
- 确定大动脉置换 (AVR) 的独立风险因素.
主要成果:
- 随访时间中位数为9.04年,10年,15年和20年的生存率分别为98.4%,97.9%和94.9%.
- 在15年内,AoV重新操作的自由率为59.1%,而AVR的自由率为65.7%.
- 对AVR的危险因素包括先前的气球膜整形术,使用CardioCel贴片,以及下腔膜整形术.
结论:
- 在婴儿期后的儿童中,大动脉的修复提供了有利的长期结果,高的生存率.
- 对于大多数患者来说,初始的AoV修复会推迟到成年期更换假体门的需要.
- 随后的程序通常涉及罗斯操作或重复AOV维修.
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