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Updated: Feb 20, 2026

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
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Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling

Published on: August 3, 2018

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TWIST1驱动内皮细胞到介质细胞的转变,以稳定动脉样硬化斑块

Blanca Tardajos Ayllon1, Mannekomba Diagbouga1, Ankita Das1

  • 1Centre for Microvascular Research, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

Nature communications
|February 18, 2026
PubMed
概括

内皮细胞中的Twist1促进了动脉样硬化中的斑块稳定性,挑战了关于内皮细胞转移到介质细胞的先前观点. 这一发现为心血管疾病提供了新的治疗点.

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