在古代-真核生物祖先的后裔中氧气代谢
Kathryn E Appler1, James P Lingford2, Xianzhe Gong1,3
1Department of Marine Science, Marine Science Institute, University of Texas at Austin, Port Aransas, TX, USA.
Nature
|February 18, 2026
概括
阿斯加德古生物,特别是海姆达拉古生物,是理解复杂生命的关键.
科学领域:
- 微生物学 微生物学
- 进化生物学 进化生物学
- 基因组学就是基因组学.
背景情况:
- 阿斯加德古生物被认为是复杂细胞生命起源的关键.
- 在Asgardarchaeota中的一个类别Heimdallarchaeia是已知的真核生物的最亲近的亲属.
- 以前,有限的基因组数据限制了人们对它们的生态和演变的理解.
研究的目的:
- 扩大阿斯加德古生物的基因组多样性,重点关注Heimdallarchaeia.
- 为了研究生态,进化和Himdallarchaeia的代谢能力.
- 通过结合新的基因组和代谢见解来完善真核生成模型.
主要方法:
- 海洋沉积物的大规模DNA测序.
- 生物信息分析以获得 404 Asgardarchaeota 的元基因组组装基因组.
- 代谢重建和结构预测.
主要成果:
- 136个新的Heimdallarchaeia基因组和新的血统被确定.
- Heimdallarchaeia 在全球范围内分布在海洋环境中,特别是在可变氧气的沿海沉积物中.
- 代谢分析揭示了Heimdallarchaeia中不同的协会,有氧生活方式蛋白质和新的化酶.
结论:
- Heimdallarchaeia具有独特的代谢特征,表明有氧生活方式.
- 更新的真核生成模型包括阿斯加德-真核生物祖先的气生产和有氧呼吸.
- 扩展的阿斯加德考古基因组多样性突出显示了真核生成中的生物能量因素.
相关概念视频
Oxygen Requirements and Growth Patterns
1.6K
Microorganisms exhibit diverse oxygen requirements and growth patterns driven by their metabolic strategies and environmental adaptations. Oxygen, while essential for many organisms, can also be toxic under certain conditions, shaping how microorganisms grow and survive.Oxygen Requirements of MicroorganismsMicroorganisms are classified based on their ability to use or tolerate oxygen:● Obligate aerobes like Mycobacterium tuberculosis need oxygen for energy production, as it serves as the...
1.6K
Oxygenic Photosynthesis
820
Oxygenic photosynthesis is a fundamental process in which light energy is harnessed to drive the oxidation of water, leading to the production of molecular oxygen (O₂), adenosine triphosphate (ATP), and nicotinamide adenine dinucleotide phosphate (NADPH). This process is essential for sustaining aerobic life on Earth and is primarily carried out by cyanobacteria, algae, and plants. The core of oxygenic photosynthesis lies in the thylakoid membranes, where chlorophyll pigments facilitate...
820
Eukaryotic Evolution
42.6K
The endosymbiont theory is the most widely accepted theory of eukaryotic evolution; however, its progression is still somewhat debated. According to the nucleus-first hypothesis, the ancestral prokaryote first evolved a membrane to enclose DNA and form the nucleus. Conversely, the mitochondria-first hypothesis suggests that the nucleus was formed after endosymbiosis of mitochondria.
Contrary to the endosymbiont theory, the eukaryote-first hypothesis proposes that the simpler prokaryotic and...
Contrary to the endosymbiont theory, the eukaryote-first hypothesis proposes that the simpler prokaryotic and...
42.6K
Peroxisomes and Mitochondria
98.4K
Peroxisomes and mitochondria are two important oxygen-utilizing organelles in eukaryotic cells. Mitochondria carry out cellular respiration—the process that converts energy from food into ATP. Peroxisomes carry out a variety of functions, primarily breaking down different substances, such as fatty acids.
The peroxisome is a single membrane-bound cellular organelle that can perform several different functions, including lipid metabolism and chemical detoxification. The enzymes within...
The peroxisome is a single membrane-bound cellular organelle that can perform several different functions, including lipid metabolism and chemical detoxification. The enzymes within...
98.4K
Anoxygenic Photosynthesis
1.4K
Anoxygenic photosynthesis is a phototrophic process that captures light energy to drive carbon fixation without producing molecular oxygen. Unlike oxygenic photosynthesis, which utilizes water as an electron donor and releases oxygen, anoxygenic phototrophs use alternative electron donors such as hydrogen sulfide (H₂S), elemental sulfur (S⁰), or thiosulfate (S₂O₃²⁻). This process is carried out by diverse groups of bacteria, including purple bacteria, green...
1.4K
Metabolism of Chemolithotrophs
963
Chemolithotrophs are microorganisms that obtain energy by oxidizing inorganic molecules such as hydrogen gas (H₂), ammonia (NH₃), reduced sulfur compounds (H₂S, S²⁻), and ferrous iron (Fe²⁺). Unlike heterotrophic organisms that rely on organic carbon, chemolithotrophs transfer electrons from these inorganic donors to the electron transport chain (ETC), generating a proton motive force (PMF) that drives ATP synthesis through oxidative phosphorylation.
963


